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  • Blue: Stimulants generally increase in potency to the upper left.
  • Red: Depressants generally increase in potency to the lower right.
  • Green: "Hallucinogens" are psychedelic to the left, dissociative to the right, generally less predictable down and to the right, and generally more potent towards the bottom.
  • Pink hue: The so called "antipsychotics". A new and controversial addition to the chart.
  • White: Overlap of all three main sections (Stimulants, Depressants and Hallucinogens) — Example: cannabis exhibits effects of all three sections.
  • Magenta (purple): Overlap of Stimulants (Blue) and Depressants (Red) — Example: nicotine exhibits effects of both.
  • Cyan (light blue): Overlap of Stimulants (Blue) and Psychedelic hallucinogens (Green) — Primary psychedelics exhibit a stimulant effect
  • Yellow : Overlap of Depressants (Red) and Dissociative hallucinogens (Green) — Primary dissociatives exhibit a depressant effect